Beta-Caryophyllene — Cannabis Terpene Guide
The CB2 agonist. Peppery, spicy, warm. Only terpene that directly binds a cannabinoid receptor.
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| Aroma | Black pepper · clove · cinnamon · spice · cedarwood |
| Effects | Anti-inflammatory · anxiolytic · analgesic (pain relief) · muscle relaxant · neuroprotective |
| Boiling Point | 320°F / 160°C |
| Also Found In | Black pepper · cloves · cinnamon · basil · oregano · hops |
The Science
Caryophyllene is the ONLY terpene confirmed to directly bind the CB2 cannabinoid receptor — the receptor subtype expressed in immune cells and implicated in inflammation, pain, and anxiety (Gertsch et al., 2008). This mechanism is why caryophyllene is considered a functional "dietary cannabinoid". Cultivars with dominant caryophyllene produce a grounded, calm, body-forward effect distinct from myrcene-led heavy-body sedation.
Typical THC Pairing
Caryophyllene typically co-dominant in modern hype cultivars — 0.3-0.8% in Gelato/Runtz-family flower.
Best Beta-Caryophyllene-Dominant Strains at Silk Road
Gmo Cookies
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Runtz
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White Runtz
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Rs11
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Wedding Cake
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Best For
Chronic pain, inflammation, anxiety without sedation, post-surgery recovery, muscle work.
Avoid If
You are on anti-coagulants (caryophyllene may mildly thin blood — consult your doctor).
Related Effects
FAQs about Beta-Caryophyllene
Is Beta-Caryophyllene legal in New York cannabis?
Yes — Beta-Caryophyllene is a natural terpene present in cannabis, food, and essential oils. It is not a regulated substance. Every cultivar on Silk Road NYC's shelf is NY OCM-licensed and lab-tested; terpene content is listed on COAs available in-store and on product pages.
Can you order a strain from the menu based on Beta-Caryophyllene content specifically?
Yes — text or call our store at (347) 233-3879 and ask for the current batch with highest Beta-Caryophyllene content. We have the COAs on file and our budtenders can match you to the strongest Beta-Caryophyllene cultivar we have on the wall today.
Do edibles contain Beta-Caryophyllene the same way flower does?
Some do — solventless hash-infused edibles (live rosin gummies) and full-spectrum concentrates retain the terpene profile of the source flower. Distillate-based edibles strip most terpenes out. If you want the Beta-Caryophyllene effect via edibles, ask specifically for live-rosin or full-spectrum products.
How does Beta-Caryophyllene differ from CBD?
Entirely different molecules. CBD is a cannabinoid — it binds CB1/CB2 receptors in the endocannabinoid system. Beta-Caryophyllene is a terpene — an aromatic hydrocarbon that contributes aroma and modulates the cannabis experience. They often work together in the "entourage effect" but they are not the same compound.
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